Handbook of Diagnostic Endocrinology

Endocrine diagnosis depends on more than a test result: the choice of assay, the sample, and the clinical context all shape what that result means. Handbook of Diagnostic Endocrinology, Third Edition, brings those considerations together in a laboratory-focused reference spanning endocrine and related metabolic disorders.

Its chapters connect biochemical testing with clinical and molecular perspectives, offering a structured way to consult the subject across organ systems, analytes, and specific diagnostic topics. Published in cooperation with AACC, the volume is aimed at clinical chemists, chemical pathologists, endocrinologists, senior medical technologists, and researchers working in related fields.

Start with the test—and how to interpret it

The opening chapter addresses the value and limitations of laboratory tests, including analytical and postanalytical errors, interferences, and the interpretation of changes over time. The book also considers proper sample collection and the use of biochemical tests in evaluating endocrine disorders.

From pituitary and thyroid to adrenal and reproductive systems

The organ-system section examines laboratory investigation of pituitary, thyroid, adrenal, and reproductive disorders, alongside gastroenteropancreatic neuroendocrine tumors. This organization helps readers move from a clinical area of interest toward the tests and interpretive questions relevant to it.

Follow the analytes through complex disorders

Further chapters address hypoglycemia, hyperglycemia and diabetes, lipoproteins, and calcium metabolism. The contents also extend to endocrine hypertension, malignancy-associated endocrine disorders, endocrine changes associated with AIDS, evaluation of short stature in children, pregnancy and the fetus, and disorders of sexual development.

A reference for laboratory-centered practice

Rather than treating endocrinology as a collection of isolated hormone measurements, this handbook places testing within broader diagnostic questions. It is suited to professionals and advanced readers who need a detailed reference across clinical chemistry and endocrine laboratory assessment.

For readers who work at the intersection of laboratory findings and endocrine disease, this third edition offers a wide-ranging place to consult established and specialized diagnostic topics.