Escourolle & Poirier’s Manual of Basic Neuropathology

Neuropathology connects what can be seen in nervous-system tissue with the biological processes behind disease. Escourolle & Poirier’s Manual of Basic Neuropathology offers a focused, pathology-centered tour of that terrain, pairing classic descriptions of lesions with discussion of pathophysiology, genetics, and molecular biology where relevant.

A pathology-first view of neurological disease

Edited by Françoise Gray, Charles Duyckaerts, and Umberto De Girolami, this sixth edition organizes its coverage across 14 chapters. It begins with basic pathology of the central nervous system, then examines tumors, trauma, vascular disorders, infections, prion diseases, multiple sclerosis and related inflammatory demyelinating diseases, and degenerative conditions.

From the brain to nerves, muscle, and pituitary

The scope extends beyond the central nervous system. Further chapters address acquired and hereditary metabolic diseases, congenital malformations and perinatal conditions, skeletal muscle pathology, peripheral nerve pathology, and diseases of the pituitary gland. An appendix surveys neuropathological techniques.

This breadth helps readers place different disease groups within a shared framework of pathological observation, while keeping attention on the lesions and mechanisms that define each topic.

A focused reference for medical readers

The editors position the manual for resident trainees and staff members with a foundation in neuroanatomy, neurohistology, anatomic pathology, and clinical neurology. Its deliberately concentrated approach centers on morphological findings and related biological principles; it is not intended as a substitute for clinical or radiological texts.

For students and neuroscience professionals building or refreshing their understanding of nervous-system pathology, this edition offers a structured way to revisit the field’s major disease categories.